Bikinin | GSK3-like kinase BIN2 inhibitor | Probechem Biochemicals

Chemical Structure : Bikinin

CAS No.: 188011-69-0

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Bikinin (Abrasin)

货号: PC-43092Not For Human Use, Lab Use Only.

Bikinin (Abrasin) is a plant GSK-3/Shaggy-like kinases inhibitor that activates brassinosteroid (BR) signaling downstream of the BR receptor, binds and inhibits Arabidopsis thaliana GSK3-like kinases.

规格	价格	库存
50 mg	￥980	In stock
100 mg	￥1480	In stock
250 mg	￥2280	In stock
1 g		Get quote

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生物&药学活性

Bikinin (Abrasin) is a plant GSK-3/Shaggy-like kinases inhibitor that activates brassinosteroid (BR) signaling downstream of the BR receptor, binds and inhibits Arabidopsis thaliana GSK3-like kinases.
Bikinin interferes directly with BIN2 kinase activity, also strongly inhibited the activity of the group I Arabidopsis GSK3 subfamilies, but not the ASKβ, ASKδ, and other Arabidopsis Ser/Thr kinases (AtMPK4, AtMPK6, and AtAURORA1).
Bikinin inhibits the SnRK2.3 kinase activity and its T180 phosphorylation in vivo.

物理化学性质&存储条件

分子量	273.0834
分子式	C9H9BrN2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 42 mg/mL
Chemical Name/SMILES	Butanoic acid, 4-[(5-bromo-2-pyridinyl)amino]-4-oxo-

参考文献

1. De Rybel B, et al. Chem Biol. 2009 Jun 26;16(6):594-604.

2. Cai Z, et al. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9651-6.

3. Rozhon W, et al. BMC Plant Biol. 2014 Jun 19;14:172.

Bikinin (Abrasin)

生物&药学活性

物理化学性质&存储条件

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Bikinin (Abrasin)

生物&药学活性

物理化学性质&存储条件

参考文献

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