Bicuculline | GABAA antagonist | Probechem Biochemicals

Chemical Structure : Bicuculline

CAS No.: 485-49-4

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Bicuculline ((+)-Bicuculline)

货号: PC-28342Not For Human Use, Lab Use Only.

Bicuculline ((+)-Bicuculline) is a competing neurotransmitter GABAA receptor antagonist with IC50 of 2 uM, shows neuroprotective and anticonvulsant activity.

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100 mg	￥880	In stock
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Bicuculline ((+)-Bicuculline) is a competing neurotransmitter GABAA receptor antagonist with IC50 of 2 uM, shows neuroprotective and anticonvulsant activity.

物理化学性质&存储条件

分子量	367.36
分子式	C20H17NO6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-6-((S)-6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-[1,3]dioxolo[4,5-e]isobenzofuran-8(6H)-one

参考文献

1. Johnston GA. Br J Pharmacol. 2013;169(2):328-336.

2. Huang SH, et al. Eur J Pharmacol. 2003;464(1):1-8.

Bicuculline ((+)-Bicuculline)

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物理化学性质&存储条件

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Bicuculline ((+)-Bicuculline)

生物&药学活性

物理化学性质&存储条件

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