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Bfl-1 inhibitor 25

Chemical Structure : Bfl-1 inhibitor 25

CAS No.:

Bfl-1 inhibitor 25

货号: PC-26239Not For Human Use, Lab Use Only.

Bfl-1 inhibitor 25 is a potent and irreversible cellular probe inhibitor of Bcl-2 family member Bfl-1 with FRET IC50 of 16 nM, inhibits SU-DHL-1 cell viability with EC50 of 0.21 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Bfl-1 inhibitor 25 is a potent and irreversible cellular probe inhibitor of Bcl-2 family member Bfl-1 with FRET IC50 of 16 nM, inhibits SU-DHL-1 cell viability with EC50 of 0.21 uM.

物理化学性质&存储条件

分子量 461.49
分子式 C24H26F3N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1R,2R)-2-Amino-N-(4-((R)-1-(N-(4-(trifluoromethoxy)phenyl)acrylamido)ethyl)phenyl)cyclopentane-1-Carboxamide

参考文献

1. J Henry Blackwell, et al. J Med Chem. 2026 Jan 22;69(2):1218-1246.

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