Bezisterim | | Probechem Biochemicals

Chemical Structure : Bezisterim

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Bezisterim (HE3286)

货号: PC-21972Not For Human Use, Lab Use Only.

Bezisterim (HE3286) is an orally bioavailable synthetic analogue of an active DHEA metabolite, displays both glucose-lowering and cholesterol-lowering effects.

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1 g		Get quote

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生物&药学活性

Bezisterim (HE3286) is an orally bioavailable synthetic analogue of an active DHEA metabolite, displays both glucose-lowering and cholesterol-lowering effects.
Bezisterim (HE3286) attenuates LPS- and TNFalpha-stimulated inflammation in primary murine macrophages.
Bezisterim (HE3286) downregulates inflammatory cytokine/chemokine expression in liver and adipose tissue of Zucker diabetic fatty rats.

物理化学性质&存储条件

分子量	330.47
分子式	C21H30O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	17alpha-pregn-5-en-20-yne-3beta,7beta,17-triol

参考文献

1. Kosiewicz MM, et al. Eur J Pharmacol. 2011 May 11;658(2-3):257-62.

2. Wang T, et al. J Pharmacol Exp Ther. 2010 Apr;333(1):70-80.

3. Offner H, et al. J Pharmacol Exp Ther. 2009 Jun;329(3):1100-9.

Bezisterim (HE3286)

生物&药学活性

物理化学性质&存储条件

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Bezisterim (HE3286)

生物&药学活性

物理化学性质&存储条件

参考文献

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