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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Cytochrome P450 (CYPs)-Bergaptol
Bergaptol

Chemical Structure : Bergaptol

CAS No.: 486-60-2

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Bergaptol (5-Hydroxypsoralen, 4-Hydroxybergapten)

货号: PC-45969Not For Human Use, Lab Use Only.

Bergaptol is a natural furanocoumarin that is found to be a potent inhibitor of debenzylation activity of CYP3A4 enzyme with IC50 of 24.92 uM.

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50 mg ￥580 In stock
100 mg ￥880 In stock
500 mg ￥1780 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Bergaptol is a natural furanocoumarin that is found to be a potent inhibitor of debenzylation activity of CYP3A4 enzyme with IC50 of 24.92 uM.
Bergaptol shows very good radical scavenging activity.

物理化学性质&存储条件

分子量 202.1629
分子式 C11H6O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: < 2.1 mg/mL
Chemical Name/SMILES

7H-Furo[3,2-g][1]benzopyran-7-one, 4-hydroxy-

参考文献

1. Girennavar B, et al. Bioorg Med Chem. 2007 Jun 1;15(11):3684-91.

2. Messer A, et al. Food Chem Toxicol. 2012 Mar;50(3-4):756-60.

3. Uesawa Y, et al. Pharmazie. 2011 Jul;66(7):525-8.

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