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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-Benzarone
Benzarone

Chemical Structure : Benzarone

CAS No.: 1477-19-6

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Benzarone (NSC 82134)

货号: PC-35159Not For Human Use, Lab Use Only.

Benzarone (NSC 82134) is a small molecule inhibitor of Eyes Absen (EYA) protein tyrosine phosphatase activity (IC50=17 uM, EYA3), exhibits selectivity for EYA over PTP1B.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Benzarone (NSC 82134) is a small molecule inhibitor of Eyes Absen (EYA) protein tyrosine phosphatase activity (IC50=17 uM, EYA3), exhibits selectivity for EYA over PTP1B;.
Benzarone (NSC 82134) inhibits both tumor angiogenesis and tumor growth.

物理化学性质&存储条件

分子量 266.296
分子式 C17H14O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2-ethyl-1-benzofuran-3-yl)-(4-hydroxyphenyl)methanone

参考文献

1. Wang Y, et al. Mol Cancer Ther. 2018 May 25. pii: molcanther.0057.2018.

2. Tadjuidje E, et al. PLoS One. 2012;7(4):e34806.

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