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首页-抗体和重组蛋白-Biosimilar Antibody-Bemarituzumab
Bemarituzumab

Chemical Structure : Bemarituzumab

CAS No.: 1952272-74-0

Bemarituzumab (Anti-human FGFR2b mAb, human IgG1-Kappa; FPA144)

货号: PC-Ab1033Not For Human Use, Lab Use Only.

Bemarituzumab (FPA144) is a humanized monoclonal IgG1 antibody against fibroblast growth factor receptor 2b (FGFR2b, FGFR2IIIb), selectively binds to FGFR2b, inhibits ligand binding and mediates antibody-dependent cell-mediated cytotoxicity, recruits natural killer immune cells into the tumor microenvironment to kill the tumor cell in ADCC manner..

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1 mg ¥3580 In stock
5 mg ¥7580 In stock
10 mg ¥12800 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Bemarituzumab (FPA144) is a humanized monoclonal IgG1 antibody against fibroblast growth factor receptor 2b (FGFR2b, FGFR2IIIb), selectively binds to FGFR2b, inhibits ligand binding and mediates antibody-dependent cell-mediated cytotoxicity, recruits natural killer immune cells into the tumor microenvironment to kill the tumor cell in ADCC manner.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

Bemarituzumab; FPA144; FPA 144; 1952272-74-0; FGFR2b; fibroblast growth factor receptor 2; FGFR2IIIb

参考文献

1. 1, Xiang H, et al. MAbs. 2021 Jan-Dec;13(1):1981202. 2, Xiang H, et al. Cancer Chemother Pharmacol. 2020 Nov;86(5):595-606. 3, Cancer Discov. 2020 May;10(5):638. 4, Catenacci DVT, et al. J Clin Oncol. 2020 Jul 20;38(21):2418-2426.

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