Chemical Structure : Bemarituzumab
CAS No.: 1952272-74-0
货号: PC-Ab1033Not For Human Use, Lab Use Only.
Bemarituzumab (FPA144) is a humanized monoclonal IgG1 antibody against fibroblast growth factor receptor 2b (FGFR2b, FGFR2IIIb), selectively binds to FGFR2b, inhibits ligand binding and mediates antibody-dependent cell-mediated cytotoxicity, recruits natural killer immune cells into the tumor microenvironment to kill the tumor cell in ADCC manner..
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Bemarituzumab (FPA144) is a humanized monoclonal IgG1 antibody against fibroblast growth factor receptor 2b (FGFR2b, FGFR2IIIb), selectively binds to FGFR2b, inhibits ligand binding and mediates antibody-dependent cell-mediated cytotoxicity, recruits natural killer immune cells into the tumor microenvironment to kill the tumor cell in ADCC manner.
分子量 | ||
分子式 | Human IgG1-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Bemarituzumab; FPA144; FPA 144; 1952272-74-0; FGFR2b; fibroblast growth factor receptor 2; FGFR2IIIb |
1. 1, Xiang H, et al. MAbs. 2021 Jan-Dec;13(1):1981202. 2, Xiang H, et al. Cancer Chemother Pharmacol. 2020 Nov;86(5):595-606. 3, Cancer Discov. 2020 May;10(5):638. 4, Catenacci DVT, et al. J Clin Oncol. 2020 Jul 20;38(21):2418-2426.
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