Befotertinib (D-0316) | EGFR inhibitor | Probechem Biochemicals

Chemical Structure : Befotertinib

CAS No.: 1835667-63-4

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Befotertinib (D-0316, D0316)

货号: PC-38341Not For Human Use, Lab Use Only.

Befotertinib (D-0316) is an orally active, third-generation EGFR tyrosine kinase inhibitor that is selective for both EGFR-TKI sensitizing and T790M resistance mutations in NSCLC.

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10 mg	￥2280	In stock
25 mg	￥3880	In stock
50 mg	￥5980	In stock
100 mg		Get quote

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Befotertinib (D-0316) is an orally active, third-generation EGFR tyrosine kinase inhibitor that is selective for both EGFR-TKI sensitizing and T790M resistance mutations in NSCLC.

物理化学性质&存储条件

分子量	567.617
分子式	C29H32F3N7O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-(2,2,2-trifluoroethyl)-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide

参考文献

1. Nagasaka M, et al. J Thorac Oncol. 2021 May;16(5):740-763.

2. Jian H, et al. Oncologist. 2022 Mar 11;27(3):163-e213.

3. Shun Lu, et al. Cancer Res (2021) 81 (13_Supplement): CT170.

Befotertinib (D-0316, D0316)

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物理化学性质&存储条件

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Befotertinib (D-0316, D0316)

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物理化学性质&存储条件

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