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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-Becampanel
Becampanel

Chemical Structure : Becampanel

CAS No.: 188696-80-2

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Becampanel (AMP397, AMP 397)

货号: PC-61707Not For Human Use, Lab Use Only.

Becampanel (AMP 397) potent, competitive antagonist of the AMPA receptor (AMPAR) with IC50 of 11 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Becampanel (AMP 397) potent, competitive antagonist of the AMPA receptor (AMPAR) with IC50 of 11 nM.
    Becampanel (AMP 397) has anticonvulsant activity for the treatment of epilepsy, neuropathic pain and cerebral ischemia.

    物理化学性质&存储条件

    分子量 330.191
    分子式 C10H11N4O7P
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    ((((7-nitro-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl)amino)methyl)phosphonic acid

    参考文献

    1. Kwan P, et al. Expert Opin Emerg Drugs. 2007 Sep;12(3):407-22.

    2. Citraro R, et al. Expert Opin Ther Targets. 2014 Mar;18(3):319-34.

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