Beauvericin |CAS 26048-05-5 Probechem Biochemicals

Chemical Structure : Beauvericin

CAS No.: 26048-05-5

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Beauvericin

货号: PC-61930Not For Human Use, Lab Use Only.

Beauvericin is a cyclic hexadepsipeptide with antibiotic and insecticidal effects, shows activity against Gram-positive bacteria and mycobacteria, and is also capable of inducing programmed cell death in mammals.

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10 mg	￥2480	In stock
25 mg	￥4280	In stock
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生物&药学活性

Beauvericin is a cyclic hexadepsipeptide with antibiotic and insecticidal effects, shows activity against Gram-positive bacteria and mycobacteria, and is also capable of inducing programmed cell death in mammals.

Beauvericin causes cellular genotoxicity by producing DNA breaks, chromosomal aberrations and micronuclei, and inhibits the PI3K/AKT pathway to induce apoptosis, thereby inhibiting the growth of HCC.

Beauvericin affects immune function by inhibiting lymphocyte proliferation and interfering with the differentiation process of human monocytes into macrophages.

物理化学性质&存储条件

分子量	784
分子式	C45H57N3O9
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl]

参考文献

1. Logrieco A, et al. Appl Environ Microbiol. 1998 Aug;64(8):3084-8.

2. Tonshin AA, et al. Toxicology. 2010 Sep 30;276(1):49-57.

Beauvericin

生物&药学活性

物理化学性质&存储条件

参考文献

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Beauvericin

生物&药学活性

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