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首页-小分子抑制剂&激动剂-Apoptosis-Apoptosis Inducer-Bavachalcone
Bavachalcone

Chemical Structure : Bavachalcone

CAS No.: 28448-85-3

Bavachalcone (Broussochalcone B)

货号: PC-25628Not For Human Use, Lab Use Only.

Bavachalcone is a potent apoptosis induce, exerts anticancer activity by promoting autophagy and apoptosis in HepG2 cells, also acts as an anti-neuroinflammatory and antidepressant through the NF-κB pathway, also targets transferrin receptor (TFRC) and sensitizes gemcitabine to affect bladder cancer progression.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Bavachalcone is a potent apoptosis inducer, exerts anticancer activity by promoting autophagy and apoptosis in HepG2 cells, also acts as an anti-neuroinflammatory and antidepressant through the NF-κB pathway, also targets transferrin receptor (TFRC) and sensitizes gemcitabine to affect bladder cancer progression.

物理化学性质&存储条件

分子量 324.38
分子式 C20H20O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-1-(2,4-Dihydroxy-5-(3-methylbut-2-en-1-yl)phenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one

参考文献

1. Zihao Zhang, et al. Imeta. 2025 Aug 17;4(5):e70071.

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