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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-CFTR-Bamocaftor potassium
Bamocaftor potassium

Chemical Structure : Bamocaftor potassium

CAS No.: 2204245-47-4

Bamocaftor potassium (VX-659 potassium)

货号: PC-72974Not For Human Use, Lab Use Only.

Bamocaftor (VX-659) is a next-generation CFTR corrector, restores F508del-CFTR protein function.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Bamocaftor (VX-659) is a next-generation CFTR corrector, restores F508del-CFTR protein function.

    物理化学性质&存储条件

    分子量 629.735
    分子式 C28H31F3N5O4S.K
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    3-Pyridinecarboxamide, N-(phenylsulfonyl)-6-[3-[2-[1-(trifluoromethyl)cyclopropyl]ethoxy]-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethyl-1-pyrrolidinyl]-, potassium salt (1:1)

    参考文献

    1. Davies JC, et al. N Engl J Med. 2018 Oct 25;379(17):1599-1611.

    2. Taylor-Cousar JL, et al. ERJ Open Res. 2019 Jun 17;5(2):00082-2019.

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