Chemical Structure : Bamocaftor
CAS No.: 2204245-48-5
货号: PC-72975Not For Human Use, Lab Use Only.
Bamocaftor (VX-659) is a next-generation CFTR corrector, restores F508del-CFTR protein function.
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Bamocaftor (VX-659) is a next-generation CFTR corrector, restores F508del-CFTR protein function.
分子量 | 591.65 | |
分子式 | C28H32F3N5O4S | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
N-(Phenylsulfonyl)-6-[3-[2-[1-(trifluoromethyl)cyclopropyl]ethoxy]-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethyl-1-pyrrolidinyl]-3-pyridinecarboxamid |
1. Davies JC, et al. N Engl J Med. 2018 Oct 25;379(17):1599-1611.
2. Taylor-Cousar JL, et al. ERJ Open Res. 2019 Jun 17;5(2):00082-2019.
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