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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-CFTR-Bamocaftor
Bamocaftor

Chemical Structure : Bamocaftor

CAS No.: 2204245-48-5

Bamocaftor (VX-659, VX659)

货号: PC-72975Not For Human Use, Lab Use Only.

Bamocaftor (VX-659) is a next-generation CFTR corrector, restores F508del-CFTR protein function.

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1 mg ¥3780 In stock
5 mg ¥7980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Bamocaftor (VX-659) is a next-generation CFTR corrector, restores F508del-CFTR protein function.

物理化学性质&存储条件

分子量 591.65
分子式 C28H32F3N5O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(Phenylsulfonyl)-6-[3-[2-[1-(trifluoromethyl)cyclopropyl]ethoxy]-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethyl-1-pyrrolidinyl]-3-pyridinecarboxamid

参考文献

1. Davies JC, et al. N Engl J Med. 2018 Oct 25;379(17):1599-1611.

2. Taylor-Cousar JL, et al. ERJ Open Res. 2019 Jun 17;5(2):00082-2019.

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