Bamlanivimab | Anti-SARS-CoV-2 Spike mAb | Probechem Biochemicals

Chemical Structure : Bamlanivimab

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Bamlanivimab (LY-CoV555, LY3819253, Ab169)

货号: PC-38875Not For Human Use, Lab Use Only.

规格	价格	库存	数量
1 mg		Get quote
5 mg		Get quote
10 mg		Get quote
25 mg		Get quote
100 mg		Get quote

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生物&药学活性

Bamlanivimab (LY-CoV555) is a potent, recombinant, neutralizing human IgG1 monoclonal antibody (mAb) against the spike protein of SARS-CoV-2, binds to SARS-CoV-2 spike protein RBD and prevents its interaction with ACE2.
LY-CoV555 pretreatment reduces viral replication and load in the lower respiratory tract of rhesus macaques challenged with SARS-CoV-2.
LY-CoV555 displayed high protection potency, supporting its clinical development and testing as a therapeutic for the treatment and prevention of COVID-19.

Isotype: IgG1-kappa.
Anti-[human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein], human monoclonal antibody.

物理化学性质&存储条件

分子量
分子式
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES

参考文献

1. Chen P, et al. N Engl J Med. 2021 Jan 21;384(3):229-237.

2. Bryan E Jones, et al. Sci Transl Med. 2021 May 12;13(593):eabf1906.

3. Jones BE, et al. bioRxiv. 2020 Oct 9:2020.09.30.318972.

Bamlanivimab (LY-CoV555, LY3819253, Ab169)

生物&药学活性

物理化学性质&存储条件

参考文献

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Bamlanivimab (LY-CoV555, LY3819253, Ab169)

生物&药学活性

物理化学性质&存储条件

参考文献

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