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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-Balomenib
Balomenib

Chemical Structure : Balomenib

CAS No.: 2939850-17-4

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Balomenib (Balamenib, ZE63-0302)

货号: PC-24113Not For Human Use, Lab Use Only.

Balomenib (Balamenib, ZE63-0302) is an oral small molecule inhibitor of the menin-KMT2A interaction with IC50 of <75 nM, inhibits the growth of MV4-11 (CC50 < 0.1 μM), MOLM-13 (CC50 0.1~0.5 μM) and HEK293 (CC50 < 2 μM).

规格 价格 库存 数量
5 mg ￥3980 In stock
10 mg ￥5980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Balomenib (Balamenib, ZE63-0302) is an oral small molecule inhibitor of the menin-KMT2A interaction with IC50 of <75 nM, inhibits the growth of MV4-11 (CC50 < 0.1 μM), MOLM-13 (CC50 0.1~0.5 μM) and HEK293 (CC50 < 2 μM).

物理化学性质&存储条件

分子量 617.68
分子式 C33H34F3N7O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-4-methyl-1-((5-oxomorpholin-2-yl)methyl)-5-((2-(6-(2,2,2-trifluoroethyl)quinazolin-4-yl)-2,7-diazaspiro[3.5]nonan-7-yl)methyl)-1H-indole-2-carbonitrile

参考文献

1. Patent WO2023107696 A2.

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