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Balapiravir

Chemical Structure : Balapiravir

CAS No.: 690270-29-2

Balapiravir (R-1626, R1626, Ro 4588161, Ro-4588161)

货号: PC-42588Not For Human Use, Lab Use Only.

Balapiravir (R-1626, Ro 4588161) is the prodrug of R1479, a potent, specific and oral HCV NS5B polymerase inhibitor.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Balapiravir (R-1626, Ro 4588161) is the prodrug of R1479, a potent, specific and oral HCV NS5B polymerase inhibitor.
Balapiravir demonstrates strong capacity to inhibit HCV replication in vitro and in vivo, without the rapid development of viral resistance.

物理化学性质&存储条件

分子量 494.4983
分子式 C21H30N6O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 100 mg/mL

Chemical Name/SMILES

Cytidine, 4'-C-azido-, 2',3',5'-tris(2-methylpropanoate)

参考文献

1. Roberts SK, et al. Hepatology. 2008 Aug;48(2):398-406.

2. McCown MF, et al. Antimicrob Agents Chemother. 2008 May;52(5):1604-12.

3. Chen YL, et al. J Virol. 2014 Feb;88(3):1740-7.

4. Toniutto P, et al. IDrugs. 2008 Oct;11(10):738-49.

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