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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-GABA Receptor-Baclofen
Baclofen

Chemical Structure : Baclofen

CAS No.: 1134-47-0

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Baclofen

货号: PC-46124Not For Human Use, Lab Use Only.

Baclofen is a derivative of the neurotransmitter GABA that acts as a GABAB receptor agonist.

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5 g ￥1380 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Baclofen is a derivative of the neurotransmitter GABA that acts as a GABAB receptor agonist.
Baclofen also blocks α2δ subunit-containing voltage-dependent calcium channel (VDCC) with Ki of 156 uM.
Baclofen is a neurotransmitter inhibitor by blocking the release of excitatory transmitters.
Baclofen serves as a central nervous system depressant and skeletal muscle relaxant.

物理化学性质&存储条件

分子量 213.6608
分子式 C10H12ClNO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: < 7.8 mg/mL
Chemical Name/SMILES

Benzenepropanoic acid, β-(aminomethyl)-4-chloro-

参考文献

1. Zvejniece L, et al. Pharmacol Biochem Behav. 2015 Oct;137:23-9.

2. Carter LP, et al. Pharmacol Ther. 2009 Jan;121(1):100-14.

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