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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Heat Shock Protein (HSP)-BX-2819
BX-2819

Chemical Structure : BX-2819

CAS No.: 1184181-50-7

BX-2819 (BX2819)

货号: PC-21297Not For Human Use, Lab Use Only.

BX-2819 is a potent, selective Hsp90 inhibitor with KD of 16.4 nM for human Hsp90α, also is a potent B. burgdorferi high-temperature protein G (Bb HtpG) with KD of 12 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BX-2819 is a potent, selective Hsp90 inhibitor with KD of 16.4 nM for human Hsp90α, also is a potent B. burgdorferi high-temperature protein G (Bb HtpG) with KD of 12 nM.

物理化学性质&存储条件

分子量 428.51
分子式 C21H24N4O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

ethyl (4-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-thioxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)benzyl)carbamate

参考文献

1. Dave L Carlson, et al. Cell Chem Biol. 2023 Oct 26:S2451-9456(23)00340-9.

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