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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-BW-723C86
BW-723C86

Chemical Structure : BW-723C86

CAS No.: 160521-72-2

BW-723C86 (BW 723C86, BW723C86)

货号: PC-60816Not For Human Use, Lab Use Only.

BW-723C86 is a potent, selective 5-HT2B receptor agonist with pKi of 7.1, >10-fold selectivity over 5-HT2A, 5-HT2C, and other 5-HT subtypes.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BW-723C86 is a potent, selective 5-HT2B receptor agonist with pKi of 7.1, >10-fold selectivity over 5-HT2A, 5-HT2C, and other 5-HT subtypes.
BW-723C86 exerts an appreciable anxiolytic-like profile in a rat social interaction test, causes hyperphagia and reduced grooming in rats.

物理化学性质&存储条件

分子量 322.85
分子式 C16H18N2OS.HCl
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

α-methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanamine hydrochloride

参考文献

1. Kennett GA, et al. Neuropharmacology. 1997 Feb;36(2):233-9.

2. Kennett GA, et al. Br J Pharmacol. 1996 Apr;117(7):1443-8.

3. Ellis ES, et al. Br J Pharmacol. 1995 Jan;114(2):400-4.

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