BVT-2733 |CAS:376640-41-4 Probechem Biochemicals

Chemical Structure : BVT-2733

CAS No.: 376640-41-4

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BVT-2733 (BVT2733;BVT 2733)

货号: PC-45406Not For Human Use, Lab Use Only.

BVT-2733 (BVT2733) is a non-steroidal, isoform-selective inhibitor of mouse 11β-HSD1 with Ki of 1 uM.

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10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥3280	In stock
100 mg		Get quote

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生物&药学活性

BVT-2733 (BVT2733) is a non-steroidal, isoform-selective inhibitor of mouse 11β-HSD1 with Ki of 1 uM.
BVT-2733 displays >20-fold selectivity over 11β-HSD2.
BVT-2733 lowers hepatic PEPCK and glucose-6-phosphatase mRNA, blood glucose and serum insulin concentrations in a hyperglycaemic and hyperinsulinaemic mouse model.

物理化学性质&存储条件

分子量	428.9566
分子式	C17H21ClN4O3S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzenesulfonamide, 3-chloro-2-methyl-N-[4-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-2-thiazolyl]-

参考文献

1. Alberts P, et al. Diabetologia. 2002 Nov;45(11):1528-32.

2. Alberts P, et al. Endocrinology. 2003 Nov;144(11):4755-62.

3. Wang L, et al. PLoS One. 2012;7(7):e40056.

BVT-2733 (BVT2733;BVT 2733)

生物&药学活性

物理化学性质&存储条件

参考文献

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BVT-2733 (BVT2733;BVT 2733)

生物&药学活性

物理化学性质&存储条件

参考文献

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