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首页-小分子抑制剂&激动剂-Tyrosine Kinase-Focal Adhesion Kinase (FAK)-BSJ-04-175
BSJ-04-175

Chemical Structure : BSJ-04-175

CAS No.: 2414478-49-0

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BSJ-04-175

货号: PC-20683Not For Human Use, Lab Use Only.

BSJ-04-175 is a potent, selective focal adhesion kinase (FAK, protein tyrosine kinase 2 or PTK2) inhibitor with biochemical IC50 of 22 nM, 30-fold selectivity over PYK2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BSJ-04-175 is a potent, selective focal adhesion kinase (FAK, protein tyrosine kinase 2 or PTK2) inhibitor with biochemical IC50 of 22 nM, 30-fold selectivity over PYK2.

    物理化学性质&存储条件

    分子量 541.62
    分子式 C29H34F3N5O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    O=C(NC)C1=CC=CC=C1NC2=CC(NC3=CC(C)=C(C4CCNCC4)C=C3OC(C)C)=NC=C2C(F)(F)F

    参考文献

    1. Eriko Koide, et al. Chembiochem. 2023 Apr 23;e202300141.

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