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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-BRD9539
BRD9539

Chemical Structure : BRD9539

CAS No.: 1374601-41-8

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BRD9539 (BRD 9539)

货号: PC-49729Not For Human Use, Lab Use Only.

BRD9539 is a small molecule inhibitor of histone hethyltransferase of G9a (euchromatin histone methyltransferase 2, EHMT2) with IC50 of 6.3 uM.

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10 mg ￥980 In stock
25 mg ￥1580 In stock
50 mg ￥2580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BRD9539 is a small molecule inhibitor of histone hethyltransferase of G9a (euchromatin histone methyltransferase 2, EHMT2) with IC50 of 6.3 uM.
BRD9539 also inhibits PRC2 activity with a similar IC50, displays no inhibition aginst SUV39H1 and DNMT1.
BRD9539 is a more potent biochemical inhibitor than its methyl-ester analogue BRD4770.

物理化学性质&存储条件

分子量 399.45
分子式 C24H21N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-benzamido-1-(3-phenylpropyl)-1H-benzo[d]imidazole-5-carboxylic acid

参考文献

1. Yuan Yuan, et al. ACS Chem Biol. 2012 Jul 20;7(7):1152-7.

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