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首页-小分子抑制剂&激动剂-Epigenetics-HDAC-BRD 8184
BRD 8184

Chemical Structure : BRD 8184

CAS No.: 1423058-83-6

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BRD 8184 (BRD8184)

货号: PC-62465Not For Human Use, Lab Use Only.

BRD 8184 is a potent, selective HDAC6 inhibitor with IC50 of 8 nM, weakly inhibits HDAC2 and HDAC8 (IC50=0.34 and 1.33 uM),has no activity for HDAC4 (IC50>30 uM)..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BRD 8184 is a potent, selective HDAC6 inhibitor with IC50 of 8 nM, weakly inhibits HDAC2 and HDAC8 (IC50=0.34 and 1.33 uM),has no activity for HDAC4 (IC50>30 uM).

    物理化学性质&存储条件

    分子量 285.303
    分子式 C15H15N3O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N1-hydroxy-N4-(2-(pyridin-4-yl)ethyl)terephthalamide

    参考文献

    1. Wagner FF, et al. J Med Chem. 2013 Feb 28;56(4):1772-6.

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