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首页-小分子抑制剂&激动剂-Epigenetics-CRISPR/Cas9-BRD7586
BRD7586

Chemical Structure : BRD7586

CAS No.: 895460-70-5

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BRD7586 (BRD 7586)

货号: PC-49532Not For Human Use, Lab Use Only.

BRD7586 (BRD 7586) is a potent, cell-permeable small-molecule inhibitor of SpCas9 with Kd value of 0.52 uM.

规格 价格 库存 数量
10 mg ￥1980 In stock
25 mg ￥2980 In stock
50 mg ￥4580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BRD7586 (BRD 7586) is a potent, cell-permeable small-molecule inhibitor of SpCas9 with Kd value of 0.52 uM.
BRD7586 enhanced SpCas9 specificity and its activity was independent of the genomic loci, DNA-repair pathway or mode of nuclease delivery.

物理化学性质&存储条件

分子量 407.887
分子式 C17H14ClN3O3S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-((4-chlorophenyl)sulfonyl)-N-(4-(pyridin-4-yl)thiazol-2-yl)propanamide

参考文献

1. Donghyun Lim, et al. Nat Cell Biol. 2022 Nov 17. doi: 10.1038/s41556-022-01005-8.

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