欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-BRD6257
BRD6257

Chemical Structure : BRD6257

CAS No.:

加入收藏

BRD6257

货号: PC-24296Not For Human Use, Lab Use Only.

BRD6257 is a potent, selective serine/threonine phosphatase PPM1D (Wip1, PP2Cδ) inhibitor with IC50 of 5 nM in LC-MS p38 MAPK assays.

规格 价格 库存 数量
50 mg Get quote
100 mg Get quote
250 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BRD6257 is a potent, selective serine/threonine phosphatase PPM1D (Wip1, PP2Cδ) inhibitor with IC50 of 5 nM in LC-MS p38 MAPK assays.
Oral administration of BRD6257 inhibits PPM1D and activates the p53 pathway in vivo comparable to GSK2830371.

物理化学性质&存储条件

分子量 550.53
分子式 C24H22F4N6O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2S)-3-(3,3-difluorocyclopentyl)-N-(4-(difluoromethyl)phenyl)-2-((7-(5-methyloxazol-2-yl)-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)amino)propanamide

参考文献

1. Shaw S, et al. iScience. 2025 Feb 20;28(3):112069.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: