BRD50837 |CAS:1314295-24-3 Probechem Biochemicals

Chemical Structure : BRD50837

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BRD50837 (BRD 50837)

货号: PC-62851Not For Human Use, Lab Use Only.

BRD50837 is a potent, selective, small-molecule inhibitor of the Sonic Hedgehog (Shh) pathway with EC50 of 90 nM, partially lowers Gli1 expression at concentrations of 2 uM, a useful probe of Shh signaling pathway. .

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生物&药学活性

BRD50837 is a potent, selective, small-molecule inhibitor of the Sonic Hedgehog (Shh) pathway with EC50 of 90 nM, partially lowers Gli1 expression at concentrations of 2 uM, a useful probe of Shh signaling pathway.

物理化学性质&存储条件

分子量	550.067
分子式	C26H32ClN3O6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((2R,3S)-2-(((4-chloro-N-methylphenyl)sulfonamido)methyl)-5-((R)-1-hydroxypropan-2-yl)-3-methyl-6-oxo-3,4,5,6-tetrahydro-2H-benzo[b][1,5]oxazocin-10-yl)cyclopropanecarboxamide

参考文献

1. Schaefer GI, et al. J Am Chem Soc. 2013 Jul 3;135(26):9675-80.

BRD50837 (BRD 50837)

生物&药学活性

物理化学性质&存储条件

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BRD50837 (BRD 50837)

生物&药学活性

物理化学性质&存储条件

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