BRD4 degrader ZZ2

Chemical Structure : BRD4 degrader ZZ2

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货号: PC-26563Not For Human Use, Lab Use Only.

BRD4 degrader ZZ2 is CTLH-dependent BRD4 BD1 molecular glue degrader with DC50 of 169 nM in Jurkat cells, bridges YPEL5 and BRD4 BD1.

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BRD4 degrader ZZ2 is CTLH-dependent BRD4 BD1 molecular glue degrader with DC50 of 169 nM in Jurkat cells, bridges YPEL5 and BRD4 BD1.

分子量	692.60
分子式	C30H28Cl2FN5O5S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	tert-butyl (S)-2-(4-(4-(3,5-dichloro-4-(fluorosulfonyl)benzamido)phenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate

1. Zhuang Z, et al. Nat Chem Biol. 2026 Apr 6. doi: 10.1038/s41589-026-02182-5.