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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-GSK-3-BRD1172
BRD1172

Chemical Structure : BRD1172

CAS No.: 1597438-86-2

BRD1172 (BRD-1172)

货号: PC-62878Not For Human Use, Lab Use Only.

BRD1172 is a highly selective, potent, reversible, ATP-competitive GSK3 inhibitor with IC50 of 3 nM/10 nM for GSK3α/GSK3β, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BRD1172 is a highly selective, potent, reversible, ATP-competitive GSK3 inhibitor with IC50 of 3 nM/10 nM for GSK3α/GSK3β, respectively.

    物理化学性质&存储条件

    分子量 391.394
    分子式 C20H20F3N3O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (4R)-4-(2-methoxyphenyl)-7,7-dimethyl-3-(trifluoromethyl)-2,4,6,8-tetrahydro-1H-pyrazolo[3,4-b]quinolin-5-one

    参考文献

    1. Wagner FF, et al. ACS Chem Biol. 2016 Jul 15;11(7):1952-63.

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