BRD-IN-17 |CAS:1914047-59-8 Probechem Biochemicals

Chemical Structure : BRD-IN-17

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BRD-IN-17

货号: PC-62278Not For Human Use, Lab Use Only.

BRD-IN-17 is a cell permeable, family VIII bromodomain tool compound with additional PB1(2) activity over and above that of PFI-3.

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生物&药学活性

BRD-IN-17 is a cell permeable, family VIII bromodomain tool compound with additional PB1(2) activity over and above that of PFI-3.
BRD-IN-17 attenuates adipocyte differentiation and dramatically decreases lipid accumulation.
BRD-IN-17 is a first in class chemical probe for Family VIII bromodomains.

物理化学性质&存储条件

分子量	362.433
分子式	C21H22N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-3-((6S,9R)-4-(cyclopropylamino)-6,7,8,9-tetrahydro-5H-6,9-epiminocyclohepta[d]pyrimidin-10-yl)-1-(2-hydroxyphenyl)prop-2-en-1-one

参考文献

1. Gerstenberger BS, et al. J Med Chem. 2016 May 26;59(10):4800-11.

BRD-IN-17

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BRD-IN-17

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