BRAF inhibitor 13 |CAS:1093100-40-3 Probechem Biochemicals

Chemical Structure : BRAF inhibitor 13

CAS No.: 1093100-40-3

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BRAF inhibitor 13 (BRAF-IN-13)

货号: PC-70025Not For Human Use, Lab Use Only.

A potent and selective B-Raf inhibitor with IC50 of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.

规格	价格	库存
5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

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生物&药学活性

BRAF inhibitor 13 (BRAF-IN-13) is a potent and selective B-Raf inhibitor with IC50 of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.
BRAF inhibitor 13 (BRAF-IN-13) induces proliferation and hyperplasia in normal tissues of mice.

物理化学性质&存储条件

分子量	478.944
分子式	C26H19ClN8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N5-(3-(9H-purin-6-yl)pyridin-2-yl)-N1-(4-chlorophenyl)-6-methylisoquinoline-1,5-diamine

参考文献

1. Wang X, et al. J Med Chem. 2012 Sep 13;55(17):7332-41.

BRAF inhibitor 13 (BRAF-IN-13)

生物&药学活性

物理化学性质&存储条件

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BRAF inhibitor 13 (BRAF-IN-13)

生物&药学活性

物理化学性质&存储条件

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