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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Complement System-BR103
BR103

Chemical Structure : BR103

CAS No.: 1434873-26-3

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BR103 (BR 103)

货号: PC-61771Not For Human Use, Lab Use Only.

BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 nM.
    BR103 displays high selectivity for C3aR over C5aR.
    BR103 induces paw oedema and mast cell activation in vivo in rats.

    物理化学性质&存储条件

    分子量 448.527
    分子式 C24H28N6O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (2-benzhydryl-5-methyl-1H-imidazole-4-carbonyl)-L-arginine

    参考文献

    1. Lohman RJ, et al. Nat Commun. 2017 Aug 24;8(1):351.

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