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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-HCN Channel-BPU-11
BPU-11

Chemical Structure : BPU-11

CAS No.: 909664-41-1

BPU-11 (Biphenyl urea compound 11)

货号: PC-38512Not For Human Use, Lab Use Only.

BPU-11 is a novel specific HCN4 channel c-linker pocket (CLP) ligand and modulator, completely abolishing the cAMP-induced shift in V1/2 (k1/2=0.42 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

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BPU-11 is a novel specific HCN4 channel c-linker pocket (CLP) ligand and modulator, completely abolishing the cAMP-induced shift in V1/2 (k1/2=0.42 uM).

物理化学性质&存储条件

分子量 501.63
分子式 C32H31N5O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-{1-[(3-Cyanophenyl)methyl]piperidin-4-yl}-3-(2-phenylphenyl)-1-(pyridin-3-ylmethyl)urea

参考文献

1. Marco Lolicato, et al. Nat Chem Biol. 2014 Jun;10(6):457-62.

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