BPTF inhibitor BZ1 | BPTF inhibitor | Probechem Biochemicals

Chemical Structure : BPTF inhibitor BZ1

CAS No.: 2766623-38-3

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BPTF inhibitor BZ1 (BPTF-IN-BZ1)

货号: PC-72758Not For Human Use, Lab Use Only.

BPTF inhibitor BZ1 is a potent, selective, cell-active inhibitor of bromodomain PHD finger transcription factor (BPTF) with Kd of 6.3 nM, >350-fold selectivity over BET bromodomains.

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5 mg	￥1580	In stock
10 mg	￥2480	In stock
25 mg	￥4280	In stock
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100 mg		Get quote

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生物&药学活性

BPTF inhibitor BZ1 is a potent, selective, cell-active inhibitor of bromodomain PHD finger transcription factor (BPTF) with Kd of 6.3 nM, >350-fold selectivity over BET bromodomains.
BPTF inhibitor BZ1 sensitizes 4T1 breast cancer cells to doxorubicin but not BPTF knockdown cells, suggesting a specificity to BPTF.

物理化学性质&存储条件

分子量	278.74
分子式	C13H15ClN4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-((4-(2-Aminoethyl)phenyl)amino)-4-chloro-2-methylpyridazin-3(2H)-one

参考文献

1. Huda Zahid, et al. J Med Chem. 2021 Sep 23;64(18):13902-13917.

BPTF inhibitor BZ1 (BPTF-IN-BZ1)

生物&药学活性

物理化学性质&存储条件

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BPTF inhibitor BZ1 (BPTF-IN-BZ1)

生物&药学活性

物理化学性质&存储条件

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