BPTF inhibitor BZ1

Chemical Structure : BPTF inhibitor BZ1

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货号: PC-72758Not For Human Use, Lab Use Only.

BPTF inhibitor BZ1 is a potent, selective, cell-active inhibitor of bromodomain PHD finger transcription factor (BPTF) with Kd of 6.3 nM, >350-fold selectivity over BET bromodomains.

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25 mg		Get quote
100 mg		Get quote
250 mg		Get quote
1 g		Get quote

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生物&药学活性

BPTF inhibitor BZ1 is a potent, selective, cell-active inhibitor of bromodomain PHD finger transcription factor (BPTF) with Kd of 6.3 nM, >350-fold selectivity over BET bromodomains.
BPTF inhibitor BZ1 sensitizes 4T1 breast cancer cells to doxorubicin but not BPTF knockdown cells, suggesting a specificity to BPTF.

物理化学性质&存储条件

分子量	278.74
分子式	C13H15ClN4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 Month
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Chemical Name/SMILES

参考文献

1. Huda Zahid, et al. J Med Chem. 2021 Sep 23;64(18):13902-13917.