BPR2-D2

Chemical Structure : BPR2-D2

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货号: PC-24923Not For Human Use, Lab Use Only.

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50 mg		Get quote
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250 mg		Get quote

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生物&药学活性

BPR2-D2 is a small molecule inhibitor against influenza virus with excellent antiviral efficacy for the oseltamivir-resistant virus (EC50= 0.021 to 0.040 uM), may target viral ribonucleoproteins (RNPs) for viral RNA synthesis, also inhibits SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) with IC50 of 4.6 uM.
BPR2-D2 inhibits 100% of the virus-induced CPE at a concentration of 0.05 µM.
BPR2-D2 also exhibits a broad antiviral spectrum against various strains of influenza A and influenza B viruses.
BPR2-D2 has previously shown notable anti-influenza activity and broad-spectrum inhibitory effects against RNA viruses.
BPR2-D2 effectively inhibits SARS-CoV-2 by modulating its RdRp function.

物理化学性质&存储条件

分子量	380.40
分子式	C25H16O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-benzoyl-4-methyl-9-phenyl-2H-furo[2,3-h]chromen-2-one

参考文献

1. Shih SR, et al. J Antimicrob Chemother. 2010 Jan;65(1):63-71.

2. Tang WF, et al. Biomed Pharmacother. 2025 Jun 20;189:118252.

BPR2-D2

生物&药学活性

物理化学性质&存储条件

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BPR2-D2

生物&药学活性

物理化学性质&存储条件

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