BP 897 | D3R agonist | Probechem Biochemicals

Chemical Structure : BP 897

CAS No.: 314776-92-6

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BP 897 (BP-897, BP-897)

货号: PC-61736Not For Human Use, Lab Use Only.

BP 897 is the first, potent, selective partial dopamine D3 receptor agonist with Ki of 0.92 nM.

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50 mg	￥3680	In stock
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生物&药学活性

BP 897 is the first, potent, selective partial dopamine D3 receptor agonist with Ki of 0.92 nM.
BP 897 displays 70 times lower affinity for D2 (Ki=61 nM), low affinities for D1 and D4 (Ki= 3 and 0.3 uM) and α1 and α2 adrenergic receptor (Ki=60 and 83 nM), negligible affinities (Ki>1 uM) for muscarinic, histamine and opiate receptors.
BP 897 inhibits cocaine-seeking behaviour that depends upon the presentation of drug-associated cues, without having any intrinsic, primary rewarding effects.

物理化学性质&存储条件

分子量	417.553
分子式	C26H31N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide

参考文献

1. Pilla M, et al. Nature. 1999 Jul 22;400(6742):371-5.

2. Wood MD, et al. Eur J Pharmacol. 2000 Oct 27;407(1-2):47-51.

3. Wicke K, et al. Eur J Pharmacol. 2001 Jul 20;424(2):85-90.

BP 897 (BP-897, BP-897)

生物&药学活性

物理化学性质&存储条件

参考文献

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BP 897 (BP-897, BP-897)

生物&药学活性

物理化学性质&存储条件

参考文献

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