BNZ132-1 | IL-2/IL-15 inhibitor Probechem Biochemicals

Chemical Structure : BNZ132-1

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BNZ132-1 (QITISILSQINRVFHEKFI)

货号: PC-38316Not For Human Use, Lab Use Only.

BNZ132-1 (QITISILSQINRVFHEKFI) is a specific peptide inhibitor for the IL-2/IL-15 subfamily, directly binds to the γc molecule (CD132).

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25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

BNZ132-1 (QITISILSQINRVFHEKFI) is a specific peptide inhibitor for the IL-2/IL-15 subfamily, directly binds to the γc molecule (CD132); BNZ132-1 shows no inhibition on non-γc-cytokines. BNZ132-1 inhibits γc-cytokines using murine PT-18 cells, but not IL-4/7/21. BNZ132-1 inhibits IL-2 and -15 with IC50 of 50-500 nM in human cells (NK92 cell line and ex vivo human T cells).

物理化学性质&存储条件

分子量
分子式
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility
Chemical Name/SMILES	Sequence: QITISILSQINRVFHEKFI

参考文献

1. Toshie Nata, et al. J Biol Chem. 2015 Sep 11;290(37):22338-51.

2. T Tiffany Wang, et al. Leukemia. 2019 May;33(5):1243-1255.

3. Raya Massoud, et al. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):11030-5.

BNZ132-1 (QITISILSQINRVFHEKFI)

生物&药学活性

物理化学性质&存储条件

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BNZ132-1 (QITISILSQINRVFHEKFI)

生物&药学活性

物理化学性质&存储条件

参考文献

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