Chemical Structure : BN82002 hydrochloride
CAS No.: 1049740-43-3
货号: PC-22998Not For Human Use, Lab Use Only.
BN82002 hydrochloride is a potent Cdc25 dual specificity phosphatase inhibitor with IC50 of 2-6 uM for Cdc25A/B/C.
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---|---|---|---|
5 mg | ¥980 | In stock | |
10 mg | ¥1480 | In stock | |
25 mg | ¥2580 | In stock | |
50 mg | ¥4280 | In stock | |
100 mg | Get quote |
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BN82002 hydrochloride is a potent Cdc25 dual specificity phosphatase inhibitor with IC50 of 2-6 uM for Cdc25A/B/C.
BN82002 impairs the proliferation of tumoral cell lines and increases CDK1 inhibitory tyrosine phosphorylation, delays cell cycle progression in HeLa cells;.
BN82002 reduces growth rate of human tumor xenografts in mice.
分子量 | 395.88 | |
分子式 | C19H26ClN3O4 | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
Phenol, 4-(dimethylamino)-2-methoxy-6-[[methyl[2-(4-nitrophenyl)ethyl]amino]methyl]-, hydrochloride (1:1) |
1. Brezak MC, et al. Cancer Res. 2004 May 1;64(9):3320-5.
2. Contour-Galcéra MO, et al. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5809-12.
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