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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HCV-BMT-052
BMT-052

Chemical Structure : BMT-052

CAS No.: 1628720-84-2

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BMT-052 (BMT052, BMT 052)

货号: PC-60424Not For Human Use, Lab Use Only.

BMT-052 is a second generation, orally biovailable pan-genotypic HCV NS5B polymerase inhibitor with EC50 of 1-10 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BMT-052 is a second generation, orally biovailable pan-genotypic HCV NS5B polymerase inhibitor with EC50 of 1-10 nM.
    BMT-052 exhibits good genotype coverage, low clearance, a moderate volume of distribution and no cytotoxicity (CC50>100 uM).

    物理化学性质&存储条件

    分子量 635.6235
    分子式 C30H17D9F4N6O5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    5-(5-((2-(1,2,4-oxadiazol-3-yl)propan-2-yl-1,1,1,3,3,3-d6)carbamoyl)-6-(methoxy-d3)pyridin-3-yl)-2-(4-fluorophenyl)-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide

    参考文献

    1. Parcella K, et al. ACS Med Chem Lett. 2017 Jun 29;8(7):771-774.

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