BMT-046091 |CAS:1551401-20-7 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Others-AP2-associated Kinase 1 (AAK1)-BMT-046091

Chemical Structure : BMT-046091

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BMT-046091 (BMT046091)

货号: PC-35098Not For Human Use, Lab Use Only.

BMT-046091 (BMT046091) is a potent and selective AAK1 inhibitor with IC50 of 2.8 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BMT-046091 (BMT046091) is a potent and selective AAK1 inhibitor with IC50 of 2.8 nM.
BMT-046091 is inactive in a panel of functional or binding assays for receptors, transporters and enzymes at >5 μM.
[3H]BMT-046091 is a potent and selective radioligand to determine AAK1 distribution and target engagement.

物理化学性质&存储条件

分子量	311.385
分子式	C18H21N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-8-((2-amino-4-methylpentyl)oxy)benzo[c][2,7]naphthyridin-5(6H)-one

参考文献

1. Louis JV, et al. Neuropharmacology. 2017 May 15;118:167-174.

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BMT-046091 (BMT046091)

生物&药学活性

物理化学性质&存储条件

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BMT-046091 (BMT046091)

生物&药学活性

物理化学性质&存储条件

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