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首页-小分子抑制剂&激动剂-GPCR-Opioid Receptor-BMS 986188
BMS 986188

Chemical Structure : BMS 986188

CAS No.: 1776115-10-6

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BMS 986188 (BMS986188)

货号: PC-38532Not For Human Use, Lab Use Only.

BMS 986188 is a potent, selective positive allosteric modulator of δ-opioid receptor with EC50 of 0.05 uM in β-arrestin recruitment assays, no significant acitivity against μ-opioid receptors.

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10 mg ￥1280 In stock
25 mg ￥2180 In stock
50 mg ￥3580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BMS 986188 is a potent, selective positive allosteric modulator of δ-opioid receptor with EC50 of 0.05 uM in β-arrestin recruitment assays, no significant acitivity against μ-opioid receptors.

物理化学性质&存储条件

分子量 535.5
分子式 C30H31BrO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

9-[4-[(2-bromophenyl)methoxy]phenyl]-3,4,5,6,7,9-hexahydro-3,3,6,6-tetramethyl-1H-xanthene-1,8(2H)-dione

参考文献

1. Burford NT, et al. J Med Chem. 2015 May 28;58(10):4220-9.

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