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首页-小分子抑制剂&激动剂-Immunology/Inflammation-PD-1/PD-L1-BMS136
BMS136

Chemical Structure : BMS136

CAS No.: 1675203-24-3

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BMS136 (BMS-136)

货号: PC-49098Not For Human Use, Lab Use Only.

BMS136 is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 96.7 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BMS136 is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 96.7 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1.

    物理化学性质&存储条件

    分子量 418.493
    分子式 C25H26N2O4
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    3-((4-(((2-hydroxyethyl)amino)methyl)-3,5-dimethoxyphenoxy)methyl)-[1,1'-biphenyl]-2-carbonitrile

    参考文献

    1. Marawan Ahmed, et al. BMC Chem. 2022 Jun 27;16(1):49.

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