BMS-986189 | PD-1/PD-L1 inhibitor | Probechem Biochemicals

Chemical Structure : BMS-986189

CAS No.: 1629665-96-8

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货号: PC-22238Not For Human Use, Lab Use Only.

BMS-986189 is a macrocyclic thioether peptide antagonist of the PD-1/PD-L1 interaction with IC50 of 1.03 nM.

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BMS-986189 is a macrocyclic thioether peptide antagonist of the PD-1/PD-L1 interaction with IC50 of 1.03 nM.

分子量	1887.24
分子式	C91H131N21O21S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Glycinamide, N-(2-mercaptoacetyl)-L-tyrosyl-N-methyl-L-alanyl-L-asparaginyl-L-prolyl-3-amino-L-alanyl-L-leucyl-(4R)-4-hydroxy-L-prolyl-L-tryptophyl-(2S)-2,4-diaminobutanoyl-1-(carboxymethyl)-L-tryptophyl-N-methyl-L-norleucyl-N-methyl-L-norleucyl-L-leucyl-L-cysteinyl-, cyclic (1→14)-thioether

1. Yang J, et al. Front Oncol. 2022 Nov 17;12:992171.