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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-BMS-986163
BMS-986163

Chemical Structure : BMS-986163

CAS No.: 1801151-09-6

BMS-986163 (BMS986163)

货号: PC-35167Not For Human Use, Lab Use Only.

BMS-986163 is a water-soluble phosphate prodrug of BMS-986169, which is a novel GluN2B negative allosteric modulator (Ki=4.0 nM)..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BMS-986163 is a water-soluble phosphate prodrug of BMS-986169, which is a novel GluN2B negative allosteric modulator (Ki=4.0 nM).

    物理化学性质&存储条件

    分子量 462.458
    分子式 C23H28FN2O5P
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-((3S,4S)-3-fluoro-1-((R)-1-(4-methylbenzyl)-2-oxopyrrolidin-3-yl)piperidin-4-yl)phenyl dihydrogen phosphate

    参考文献

    1. Marcin LR, et al. ACS Med Chem Lett. 2018 Apr 13;9(5):472-477.

    2. Bristow LJ, et al. J Pharmacol Exp Ther. 2017 Dec;363(3):377-393.

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