BMS-986121 | MOR PAM | Probechem Biochemicals

Chemical Structure : BMS-986121

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BMS-986121 (BMS986121)

货号: PC-22779Not For Human Use, Lab Use Only.

BMS-986121 is a positive allosteric modulator of μ-opioid receptor (MOR) with EC50 of 1 uM for increased β-arrestin recruitment by 20 nM endomorphin-I.

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生物&药学活性

BMS-986121 is a positive allosteric modulator of μ-opioid receptor (MOR) with EC50 of 1 uM for increased β-arrestin recruitment by 20 nM endomorphin-I.

物理化学性质&存储条件

分子量	366.22
分子式	C15H9Cl2N3O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Thiazolamine, N-(2,6-dichlorophenyl)-4-(4-nitrophenyl)-

参考文献

1. Bisignano P, et al. J Chem Inf Model. 2015 Sep 28;55(9):1836-43.

2. Burford NT, et al. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10830-5.

BMS-986121 (BMS986121)

生物&药学活性

物理化学性质&存储条件

参考文献

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BMS-986121 (BMS986121)

生物&药学活性

物理化学性质&存储条件

参考文献

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