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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Notch-BMS-983970
BMS-983970

Chemical Structure : BMS-983970

CAS No.: 1584713-87-0

BMS-983970 (BMS983970)

货号: PC-43026Not For Human Use, Lab Use Only.

BMS-983970 (BMS983970) is a potent, orally active, pan-Notch inhibitor, demonstrates robust anti-tumor activity at tolerated doses in multiple tumor xenograft models..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BMS-983970 (BMS983970) is a potent, orally active, pan-Notch inhibitor, demonstrates robust anti-tumor activity at tolerated doses in multiple tumor xenograft models.

物理化学性质&存储条件

分子量 518.5032
分子式 C26H26F4N4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO

Chemical Name/SMILES

Butanediamide, 3-(cyclopropylmethyl)-N1-[(3S)-9-fluoro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-2-(3,3,3-trifluoropropyl)-, (2R,3S)-

参考文献

1. Ashvinikumar V. Gavai, et al. Abstract 1643: BMS-983970, an oral pan-Notch inhibitor for the treatment of cancer . Cancer Res October 1, 2014 74; 1643.

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