BMS-962212 | FXIa inhibitor | Probechem Biochemicals

Chemical Structure : BMS-962212

加入收藏

BMS-962212 (BMS962212)

货号: PC-62006Not For Human Use, Lab Use Only.

BMS-962212 is a potent, highly selective and reversible small molecule coagulation Factor XIa (FXIa) inhibitor with Ki of 0.7 nM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

BMS-962212 is a potent, highly selective and reversible small molecule coagulation Factor XIa (FXIa) inhibitor with Ki of 0.7 nM.
BMS-962212 displays an excellent protease selectivity profile, including thrombin, Factor Xa/VIIa/IXa/XIIa, plasma or tissue kallikrein.
BMS-962212 shows excellent preclinical efficacy in thrombosis models and aqueous solubility suitable for intravenous administration.

物理化学性质&存储条件

分子量	659.075
分子式	C32H28ClFN8O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S,E)-4-(2-(3-(3-Chloro-2-fluoro-6-(1H-tetrazol-1-yl)phenyl)-acryloyl)-5-(4-methyl-2-oxopiperazin-1-yl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamido)benzoic acid

参考文献

1. Pinto DJP, et al. J Med Chem. 2017 Dec 14;60(23):9703-9723.

2. Perera V, et al. Br J Clin Pharmacol. 2018 Jan 18. doi: 10.1111/bcp.13520.

BMS-962212 (BMS962212)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

BMS-962212 (BMS962212)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.