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首页-小分子抑制剂&激动剂-GPCR-P2Y Receptor-BMS-884775
BMS-884775

Chemical Structure : BMS-884775

CAS No.: 1557206-59-3

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BMS-884775 (BMS884775)

货号: PC-63561Not For Human Use, Lab Use Only.

BMS-884775 is a potent, selective P2Y1 antagonist with IC50 of 0.12 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BMS-884775 is a potent, selective P2Y1 antagonist with IC50 of 0.12 nM.
    BMS-884775 demonstrates similar antithrombotic efficacy with less bleeding compared with known P2Y12 antagonist prasugrel.

    物理化学性质&存储条件

    分子量 689.223
    分子式 C36H35ClF2N6O2S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    3-(5-Chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl)-1-(2-{1'-(2,2-dimethylpropyl)-5-fluoro-4-(4-fluorophenyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4'-piperidine]-1-yl}phenyl)urea

    参考文献

    1. Yang W, et al. J Med Chem. 2014 Jul 24;57(14):6150-64.

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