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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Glucokinase-BMS-820132
BMS-820132

Chemical Structure : BMS-820132

CAS No.: 1001419-18-6

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BMS-820132 (BMS820132)

货号: PC-38112Not For Human Use, Lab Use Only.

BMS-820132 (BMS 820132) is potent, selective, partial glucokinase (GK) activator with AC50 of 29 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BMS-820132 (BMS 820132) is potent, selective, partial glucokinase (GK) activator with AC50 of 29 nM.
    BMS-820132 displays promising in vivo efficacy and preclinical ADME and safety profiles for the treatment of type 2 diabetes.

    物理化学性质&存储条件

    分子量 572.559
    分子式 C26H33N6O7P
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    diethyl ((3-(3-((5-(azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1H-pyrazol-1-yl)methyl)phosphonate

    参考文献

    1. Shi Y, et al. J Med Chem. 2022 Mar 10;65(5):4291-4317.

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