BMS-394136 |CAS:343246-73-1 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-BMS-394136

Chemical Structure : BMS-394136

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BMS-394136 (BMS394136)

货号: PC-63569Not For Human Use, Lab Use Only.

BMS-394136 is a potent, selective IKur/Kv1.5inhibitor, increases atrial action potential duration (APD) and prolongs AERP but not VERP in both rabbits and beagles..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BMS-394136 is a potent, selective IKur/Kv1.5 inhibitor, increases atrial action potential duration (APD) and prolongs AERP but not VERP in both rabbits and beagles.

物理化学性质&存储条件

分子量	471.357
分子式	C24H21Cl2FN4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Pyrrolidine, 1-[[(7R)-7-(3,4-dichlorophenyl)-4,7-dihydro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl]carbonyl]-2-(4-fluorophenyl)-, (2S)- (9CI)

参考文献

1. Dezhi Xing, et al. Abstract 2515: A Selective IKur Blocker, BMS-394136 Selectively Prolongs Atrial APD and Refractoriness in Beagles and Rabbits. Circulation. 2009;120:S654.

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BMS-394136 (BMS394136)

生物&药学活性

物理化学性质&存储条件

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BMS-394136 (BMS394136)

生物&药学活性

物理化学性质&存储条件

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