BMS-3 |CAS:1338247-30-5 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-LIM Kinase (LIMK)-BMS-3

Chemical Structure : BMS-3

CAS No.: 1338247-30-5

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BMS-3 (BMS3;BMS 3)

货号: PC-45450Not For Human Use, Lab Use Only.

BMS-3 is a potent LIMK inhibitor with IC50 of 5/6 nM for LIMK1/2.

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10 mg	￥980	In stock
25 mg	￥1580	In stock
50 mg	￥2580	In stock
100 mg		Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BMS-3 is a potent LIMK inhibitor with IC50 of 5/6 nM for LIMK1/2.
BMS-3 shows cytotoxic effect and inhibits the proliferation of A549 cells with IC50 of 154 nM.

物理化学性质&存储条件

分子量	429.2712
分子式	C17H12Cl2F2N4OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 30 mg/mL
Chemical Name/SMILES	Cyclopropanecarboxamide, N-[5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-

参考文献

1. Ross-Macdonald P, et al. Mol Cancer Ther. 2008 Nov;7(11):3490-8.

2. Romarowski A, et al. Dev Biol. 2015 Sep 15;405(2):237-49.

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BMS-3 (BMS3;BMS 3)

生物&药学活性

物理化学性质&存储条件

参考文献

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BMS-3 (BMS3;BMS 3)

生物&药学活性

物理化学性质&存储条件

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